South Side facility (Knopp Biosciences) working on treatment for Lou Gehrig’s disease

It is clear to Neil Alexander that his amyotrophic lateral sclerosis is progressing.

In the little more than two years that have passed since the 48-year-old was diagnosed with the disease more commonly known as ALS or Lou Gehrig’s, his hands have weakened, his lung capacity has declined and he is beginning to have difficulty with his speech.

Over the past few months, his legs have gotten “significantly weaker,” so that he now walks with a limp, has trouble using stairs and has fallen several times, he said. He knows the fatal disease is progressing through his body, but for more than a year, he believes the progression slowed.

The reason, he thinks, is dexpramipexole.

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